Updated May 2026
Ozempic vs Saxenda
Side-by-side comparison of Ozempic (semaglutide (T2D injection)) and Saxenda (liraglutide (daily injection)) across efficacy, food restrictions, monthly cost, and Medicare Bridge coverage.
Our pick for most patients
Ozempic
Based on the data below, Ozempic wins on lower cash price ($998/mo vs $1349/mo). Your situation may differ — try the personalized matcher on the homepage or compute your real out-of-pocket with the cost calculator on each medication's detail page.
| Field | Ozempic | Saxenda |
|---|---|---|
| Route | injection · weekly | injection · daily |
| Avg weight loss | 5–8% | 5–8% |
| Food restriction | No food restriction | No food restriction |
| Cash from | $998/mo | $1349/mo |
| Savings card | — | — |
| Medicare Bridge | Tier 4 | Tier 4 |
| A1c reduction | −1.8% | — |
| FDA approved | 2017-12 | 2014-12 |
- RouteOzempicinjection · weeklySaxendainjection · daily
- Avg weight lossOzempic5–8%Saxenda5–8%
- Food restrictionOzempicNo food restrictionSaxendaNo food restriction
- Cash fromOzempic$998/moSaxenda$1349/mo
- Savings cardOzempic—Saxenda—
- Medicare BridgeOzempicTier 4SaxendaTier 4
- A1c reductionOzempic−1.8%Saxenda—
- FDA approvedOzempic2017-12Saxenda2014-12
Pick Ozempic if…
- You can't reliably do a fasting window before meds
- Cash pay matters more than peak weight loss ($998/mo cheaper)
Pick Saxenda if…
- You can't reliably do a fasting window before meds
Not sure which fits?
The 30-second matcher on the homepage scores every 2026 GLP-1 against your goals + preferences and recommends the best fit.