Updated May 2026
Foundayo vs Wegovy Tablets
Side-by-side comparison of Foundayo (orforglipron) and Wegovy Tablets (semaglutide HD-oral) across efficacy, food restrictions, monthly cost, and Medicare Bridge coverage.
Our pick for most patients
Foundayo
Based on the data below, Foundayo wins on higher peak weight loss (16% vs 15%). Your situation may differ — try the personalized matcher on the homepage or compute your real out-of-pocket with the cost calculator on each medication's detail page.
| Field | Foundayo | Wegovy Tablets |
|---|---|---|
| Route | tablet · daily | tablet · daily |
| Avg weight loss | 12–16% | 12–15% |
| Food restriction | No food OR water | Empty stomach |
| Cash from | $149/mo | $149/mo |
| Savings card | $25/mo | — |
| Medicare Bridge | $50/mo ✓ | $50/mo ✓ |
| A1c reduction | — | — |
| FDA approved | 2026-04 | 2025-12 |
- RouteFoundayotablet · dailyWegovy Tabletstablet · daily
- Avg weight lossFoundayo12–16%Wegovy Tablets12–15%
- Food restrictionFoundayoNo food OR waterWegovy TabletsEmpty stomach
- Cash fromFoundayo$149/moWegovy Tablets$149/mo
- Savings cardFoundayo$25/moWegovy Tablets—
- Medicare BridgeFoundayo$50/mo ✓Wegovy Tablets$50/mo ✓
- A1c reductionFoundayo—Wegovy Tablets—
- FDA approvedFoundayo2026-04Wegovy Tablets2025-12
Pick Foundayo if…
- You can't reliably do a fasting window before meds
- You're on Medicare and want the $50/mo Bridge price
- You want the higher peak efficacy (16% vs 15%)
Pick Wegovy Tablets if…
- You're on Medicare and want the $50/mo Bridge price
Not sure which fits?
The 30-second matcher on the homepage scores every 2026 GLP-1 against your goals + preferences and recommends the best fit.